- Virginia Counties Collection, 1600/2000, bulk 1730/189040
- University of Virginia School of Nursing, 1819/201622
- Alexandria History Collection (MS240), 1767/200817
- Atkeson-Morgan Family Papers, 1833/1923, bulk 1850/190016
- Historic newspapers collection, 1757/195716
- Jim Comstock, Newspaper Editor and Collector, Papers, 1650/2003, bulk 1850/199512
- Roy Bird Cook (1886-1961), Collector, Papers, 1679/1984, bulk 1840/196011
- Francis Harrison Pierpont (1814-1899) Papers, 1811/1949, bulk 1860/189910
- Philip S. Hench Walter Reed Yellow Fever collection, 1800/1998, bulk 1863/197410
- David Hunter Strother, Artist, Artwork and Papers, 1744/1996, bulk 1833/18879
- Galt Papers (III), 1750/19919
- Monongalia County Historical Records, 1792/1982, bulk 1878/19769
- Vaughn L. Kiger, Collector, Historical Photographs and Records regarding Morgantown, 1784/2017, bulk 1880/20109
- Willis Guy Tetrick, Jr. Genealogy Research Papers, 1708/19979
- Appalachian Prints Collection, 1839/2010, bulk 1859/19098