- Alexander Von Humboldt Portrait Print, 1855/18901
- Bailey-Law Collection, 1825/19712
- Black, Kent, and Apperson Family Papers, 1779/19841
- Brown Family Papers, 1825/1965, bulk 1850/189411
- Burrows Family Letters, 1861/18913
- Christiansburg Presbyterian Church Minute Book, 1869/18971
- Christiansburg [Virginia] Industrial Institute Historical Documents, 1866/19912
- Dickson Family Papers, 1769/19241
- Dillon, Ellett & Company Ledgers, 1871/18991
- George J. Schmutz Papers, 1868/19262
- George Washington Morgan Autograph, 1840/18901
- Gottlieb Daimler Photography Print, 1834/19001
- Graham and Robinson Account Book, 1869/18731
- Henry C. Parsons Papers, 1863/19051
- Henry Goddard Thomas Letters and Memoirs, 1868/18891