- Account Books, 1782/18954
- Ackerly Family Papers5
- Adele Goodman Clark papers, 1849/19781
- Alexander Brown Papers (I), 1815/19103
- Alexander Family Papers
1800-18906
- Alexander Von Humboldt Portrait Print, 1855/18901
- Alexandria Black Family Reunion Digital Collection, 1937/20051
- Alfred C. Garnett, Jr. Papers
1868-19451
- Alfred Spates Papers
1843-19096
- Alice and Phoebe Cary Collection
1850-18691
- Alice and Phoebe Cary Collection
1858-18901
- Allen-Kean-Laurence family letters, 1837/19601
- Appalachian Prints Collection, 1839/2010, bulk 1859/19091
- Armistead-Cocke Papers, 1680/19173
- Atkeson-Morgan Family Papers, 1833/1923, bulk 1850/19005