- Account Books, 1782/18954
- Ackerly Family Papers5
- Adele Goodman Clark papers, 1849/19781
- Alexander Brown Papers (I), 1815/19104
- Alexander Family Papers
1800-18906
- Alexander Family Papers, 1860/18671
- Alexander Von Humboldt Portrait Print, 1855/18901
- Alexandria Black Family Reunion Digital Collection, 1937/20052
- Alfred Spates Papers
1843-19096
- Alice and Phoebe Cary Collection
1852-1870, n.d.1
- Alice and Phoebe Cary Collection
1858-18901
- Allen-Kean-Laurence family letters, 1837/19601
- Appalachian Prints Collection, 1839/2010, bulk 1859/19091
- Armistead-Cocke Papers, 1680/19172
- Atkeson-Morgan Family Papers, 1833/1923, bulk 1850/19005