- Alan Clarke Railroad Research Papers, 1861/201213
- Alston Gordon Dayton Papers, 1846/19391
- Armstead L. Robinson papers, 1848/2001, bulk 1967/199210
- Blair family papers, 1821/19492
- Braxton County (W. Va.) Court Records and Miscellaneous Papers, 1830/195328
- Brooke County (W. Va.) Court Records and Miscellaneous Papers, 1780/191821
- Clarence L. Musgrave Papers, 1839/19371
- Early Records of the Mount Vernon Ladies' Association, 1853/1951, bulk 1853/18752
- Emory L. Kemp Papers regarding Industrial History, 1735/20218
- Faris, Faris, and Stephens, Architects, Records, 1890/20131
- Farrier Family Papers, 1894/19721
- Fayette County (W. Va.) Court Records and Miscellaneous Papers, 1787/1923, bulk 1870/19238
- Forbes, Anderson, and Hildebrand Families, Correspondence and Other Material, 1862/20131
- Frances Yeend, Opera Singer, Photographs, Recordings, and Papers, 1900/1990, bulk 1938/19661
- Francis H. Fife papers, 1785/2015, bulk 1940/20151