- Account Books, 1782/18952
- Ackerly Family Papers6
- Adele Goodman Clark papers, 1849/19781
- Adolphus DeBussey, Soldier, Civil War Letters, 1861/1998, bulk 1861/18713
- Albert Taylor Bledsoe and Sophia Bledsoe Herrick letters, 1858/19081
- Alexander Brown Papers (I), 1815/19103
- Alexander Family Papers
1800-18906
- Alexander Von Humboldt Portrait Print, 1855/18901
- Alexandria Black Family Reunion Digital Collection, 1937/20051
- Alfred Spates Papers
1843-19096
- Alice and Phoebe Cary Collection
1855-1870,
n.d.1
- Alice and Phoebe Cary Collection
1858-18901
- Allen-Kean-Laurence family letters, 1837/19601
- Appalachian Prints Collection, 1839/2010, bulk 1859/19092
- Armistead-Cocke Papers, 1680/19171