- U.S. Department of Commerce, Coast and Geodetic Survey, Selected Civil War Maps, 1861/18651
- U.S. Seizure and Confiscation Book (MS207), 1863/18642
- U.S. v $28, 000-Effects of R. E. Lee et al. Case Files, 1863/18662
- Umbarger Family Correspondence, 1863/18832
- Unidentified Civil War Union Soldier letter, 18651
- Union General Orders No. 190, 18632
- Union Hospital Bed Card, 1861/18652
- Union Soldier Photograph, 1861/18652
- Union Soldier [Charles] Correspondence, 1861/18648
- Union Volunteers of West Virginia Regiments, Civil War Service Records, 1861/1865262
- United Daughters of the Confederacy, Dr. Harvy Black Chapter Records, 1862/20103
- United States Army, 12th West Virginia Infantry Regiment, Records, 1862/18661
- United States District Court, Western District of Virginia, Records, 1843/18801
- United States District Court, Wheeling, Naturalization Petitions, 1844/18721
- United States Federal Nineteenth Century Government Publications, 1826/18784