- E. E. Meredith, Collector, Broadsides and Other Material regarding Jackson and Marion Counties, 1855/19511
- E. H. Hook Diary, 1820/18712
- E. L. Mathers and Max Mathers, Compilers, Monongalia County Scrapbook, 1838/19511
- E. P. Jones Letter, 18632
- E. Steadman Financial Records, 1861/18651
- E.B. Ellicott Letter, 18632
- Earhart Family Papers, 1788/192811
- Earl Gregg Swem Genealogy Collection, 1719/19826
- Earl L. Core (1902-1984) Papers, 1756/198517
- Earl L. Core, Collector, Papers, 1840/19271
- Earl and Jewell Ratliff Collection, 1860/2013, bulk 1920/19902
- Early Records of the Mount Vernon Ladies' Association, 1853/1951, bulk 1853/187577
- Eastern State Hospital Records, 1862/1957, bulk 1862/18682
- Easton-Avery Community History, 1769/19271
- Eben P. Wolcott Correspondence, 1862/18632