- A. Eliza Crane letter, 18541
- Account Books, 1782/18952
- Ackerly Family Papers4
- Adele Goodman Clark papers, 1849/19781
- Alexander Brown Papers (I), 1815/19102
- Alexander Family Papers
1800-18909
- Alexandria Black Family Reunion Digital Collection, 1937/20051
- Alfred Spates Papers
1843-19093
- Allen-Kean-Laurence family letters, 1837/19601
- Appalachian Prints Collection, 1839/2010, bulk 1859/19091
- Archibald Woods Papers, 1777/1846, bulk 1783/18463
- Armistead-Cocke Papers, 1680/19173
- Asa F. Horn Account Book and Family Correspondence, 1854/18611
- Atkeson-Morgan Family Papers, 1833/1923, bulk 1850/19002
- Austin-Twyman Papers, 1765/193910