- B. Davenport & Co. Ledger, 1841/18612
- B. Floyd Flickinger Papers, 1927/19501
- Baer Family Papers, 1744/19291
- Bailee Family Photographs, 1850/19001
- Bailey-Law Collection, 1825/19716
- Baird Family Papers, 1656/1922, bulk 1656/18485
- Baker Family Papers
1781-19217
- Baker Family Papers, 1805/19112
- Baltimore and Ohio Railroad Records, 1853/18641
- Bane Family Genealogy, 1800/19551
- Bank of Rockbridge Currency and Lexington Lottery Ticket collection, 1803/18622
- Baptismal records of enslaved and emancipated Cubans, 1838/18751
- Barb Family Papers, 1814/19801
- Barb(e) Family Genealogy, 1836/19331
- Barbara Cary Johnston Willard Scrapbook, 1800/20061