- A. H. Hand Papers, 1835/20091
- A. Willis Robertson Papers, 1921/1988, bulk 1946/19663
- Abner Johnson Leavenworth Papers, 1825/18611
- Abraham Grove Account Book, 1815/18501
- Absalom See Account Books, 1854/18691
- Adams Papers, 1782/18901
- Addie Rogers Bound Sheet Music Collection, 1827/18602
- Alabama Collection, 1823/18931
- Alexander Brown Papers (I), 1815/19107
- Alexander Brown Papers (II), 1748/19007
- Alexander Hamilton, Jr. Letters, 1832/18331
- Alexander Hugh Holmes Stuart Account Books, 1837/18571
- Alexander M. Davis Papers, 1850/18921
- Alumni Association Records, 1833/2014, bulk 1950/20051
- Amos Koontz Papers I, 1809/1965, bulk 1936/19651