- Southall Papers, 1807/1904486
- Cocke Family Papers, 1725-1939441
- Carter Family Papers, 1667/1862, bulk 1792/1861187
- Galt Papers (I), 1745/1892142
- Monongalia County (W. Va.) Court Records and Miscellaneous Papers, 1774/1954122
- Ohio County (W. Va.) Court Records and Miscellaneous Papers, 1772/1954, bulk 1777/1930115
- Ritchie-Harrison Papers, 1807/1938, bulk 1830/1870113
- Edward "Teddy" Bolton Tucker Papers, 1760/2007, bulk 1800/1900110
- Tucker-Coleman papers, 1664/1945, bulk 1770/1907106
- Restoration Files for the Historic Structures Report, 1750/2005103
- Emory L. Kemp Papers regarding Industrial History, 1735/2021100
- Austin-Twyman Papers, 1765/193998
- Sheet Music Collection, 1827/197494
- Virginia Counties Collection, 1600/2000, bulk 1730/189087
- Monroe County (W. Va.) Court Records and Miscellaneous Papers, 1751/192786