- Andrew Jackson Davis Collection, 1840/20112
- Andrew S. Core, Typescripts and Charts, 1804/18881
- Andrew Steele Fulton Account Books, 1825/18341
- Anita Cutright Burnett, Collector, Papers, 1790/19351
- Ann Lettice Murdoch Diary, 1841/18641
- Ann Smith Academy Papers, 1807/19101
- Anna Burton Ellett Collection, 1751/19321
- Anna Maria Hickman Otis Mead Chalmers family papers, 1821/189718
- Anne Atkinson Chamberlayne Collection., 1742/19633
- Anne Hulme Diary,, 1838/18502
- Annual and special reports of the Superintendent, 1840/19941
- Anthony Ware, Miscellaneous Papers, 1773/18861
- Antoine Gaujot and Julien E. Gaujot Papers, 1840/19992
- Appalachian Prints Collection, 1839/2010, bulk 1859/19092
- Appomattox Manor Music Collection, 1800/1940, bulk 1850/19101