- A. H. Hand Papers, 1835/20092
- A. Willis Robertson Papers, 1921/1988, bulk 1946/19661
- Abner Johnson Leavenworth Papers, 1825/18619
- Abolitionist Movement Collection, 1834/18882
- Abraham Grove Account Book, 1815/18502
- Accounts, 19th Century, 1836/18971
- Adam Empie Papers, 1811/2004, bulk 1811/18502
- Adam Rinica and George Rinica Account Book, 1822/18482
- Adams Papers, 1782/18902
- Addie Rogers Bound Sheet Music Collection, 1827/18603
- Alabama Collection, 1823/18932
- Alexander Brown Papers (I), 1815/19104
- Alexander Brown Papers (II), 1748/19001
- Alexander Hamilton, Jr. Letters, 1832/18331
- Alexander Hugh Holmes Stuart Account Books, 1837/18573