- Armstead L. Robinson papers, 1848/2001, bulk 1967/19921
- Bessie Rowland James Papers, 1800/19721
- Blair family papers, 1821/19492
- Braxton County (W. Va.) Court Records and Miscellaneous Papers, 1830/19534
- Brooke County (W. Va.) Court Records and Miscellaneous Papers, 1780/191829
- Emory L. Kemp Papers regarding Industrial History, 1735/20215
- Fayette County (W. Va.) Court Records and Miscellaneous Papers, 1787/1923, bulk 1870/19234
- Foulke Family Papers, 1784/19141
- Francis Harrison Pierpont Artifacts Collected by Jack Sandy Anderson, 1830/18762
- Hampden-Sydney Diploma Collection, 1775/19742
- Hampshire County (W. Va.) Court Records and Miscellaneous Papers, 1736/194916
- Historic manuscript collection, 1601/19333
- Institute for the History of Technology and Industrial Archaeology Records, 1875/2005, bulk 1980/20051
- James M. Guiher, Jr., Papers, 1835/2014, bulk 1927/19762
- Jefferson Society records, 1825/20181