- B. G. D. Moxley Account Book, 1829/18352
- B. J. Spruell Account Book, 1782/18362
- Baer Family Papers, 1744/19291
- Bailey-Law Collection, 1825/19713
- Baird Family Papers, 1656/1922, bulk 1656/18486
- Baker Family Papers
1781-192110
- Baker Family Papers, 1805/19112
- Bane Family Genealogy, 1800/19551
- Bank of Rockbridge Currency and Lexington Lottery Ticket collection, 1803/18622
- Barb Family Papers, 1814/19801
- Barbara Cary Johnston Willard Scrapbook, 1800/20061
- Barker-Cooke Papers, 1809/1889, bulk 1848/18663
- Barnes Family Papers, 1797/1926, bulk 1818/18753
- Barns Family Papers, 1816/1899, bulk 1831/18991
- Barraud Family Papers, 1799/1904, bulk 1810/18602