- Aaron Harmon Collection (MS249), 1815/18361
- Alexandria Black Family Reunion Digital Collection, 1937/20051
- Alexandria Gazette Ledgers (MS026), 1833/18666
- Alexandria History Collection (MS240), 1767/200820
- Alexandria Library Company Records (MS002), 1794/20079
- Alexandria Scrapbook Collection (MS003), 1830/18932
- Alexandria, Virginia City Records (MS019), 1750/1983, bulk 1825/18751
- Armistead Boothe Papers (MS164), 1803/19907
- Cazenove Family Papers (MS212), 1786/197020
- Chapman Family Collection (MS274), 1828/19632
- Edith Moore Sprouse Papers (MS313), 1960/20031
- Eleanor Lee Templeman Collection (MS061), 1810/19903
- Esther Holliday Green Collection (MS073), 1859/19825
- Ethelyn Cox Collection (MS287), 1956/19801
- Helen Norris Cummings Papers (MS072), 1865/19491