- Alice Rice Jaffe Papers, 1807/1950, bulk 1919/19501
- Buck Family Papers, 1807/18501
- Elie Beatty Papers, 1814/18471
- Eloise Word Skewis Papers, 1777/19071
- Finlay Forbes Ferguson Papers, 1812/19751
- Harold S. Wilson Papers, 1813/19781
- Hodges Family Papers, 1754/19791
- James Washington Singleton Papers, 1770/1975, bulk 1850/19201
- Mason C. Andrews Papers, 1777/2010, bulk 1950/19901
- Niles' Weekly Register Concerning Nat Turner Slave Rebellion, 18311
- Nineteenth Century Stethoscope, 1800/18601
- Robert Morton Hughes Papers, 1754/19501
- Rose-Tunstall Family Papers, 1809/19471
- Shipbuilding Ledger (Norfolk, Va.), 1796/18601
- The Independent Collection, 1680/19601