- Admiral John Randolph Tucker Papers, 1865/18971
- Ancella Bickley, Historian, Research Papers regarding African-Americans, 1775/2018, bulk 1970/20115
- Armistead Boothe Papers (MS164), 1803/19901
- Austin-Twyman Papers, 1765/193929
- Bailey-Law Collection, 1825/19711
- Benjamin A. Banks Papers, 1855/19741
- Black, Kent, and Apperson Family Papers, 1779/19842
- Blair family papers, 1821/19491
- Blow Family Papers, 1613/1960, bulk 1770/18753
- Borland Family Papers, 1771/19402
- Brown, Coalter, Tucker Papers (I), 1790/192913
- Brown, Coalter, Tucker Papers (II), 1791/19203
- Bushrod Washington family papers, 1662/18352
- Carter Family Papers, 1667/1862, bulk 1792/186131
- Cazenove Family Papers (MS212), 1786/19705