- Blow Family Papers, 1613/1960, bulk 1770/187559
- Austin-Twyman Papers, 1765/193955
- Emory L. Kemp Papers regarding Industrial History, 1735/202154
- Brown, Coalter, Tucker Papers (I), 1790/192952
- Archibald Woods Papers, 1777/1846, bulk 1783/184649
- Roy Bird Cook (1886-1961), Collector, Papers, 1679/1984, bulk 1840/196046
- McGavock Family Papers, 1760/188841
- Papers of the Randolph Family of Edgehill, 1732/186040
- Mildred Hassler Layman, Family and Genealogy Papers, 1750/195237
- Historic manuscript collection, 1601/193336
- Violette S. Machir, Compiler, Revolutionary War Pension Applications and Genealogies (Mason County), 1828/199536
- Haymond Family Papers, 1783/1867, bulk 1825/186733
- Tyler Family Papers, Group D, 1939/195133
- Galt Papers (III), 1750/199132
- Christian S. Hutter miscellany, 1602/194531