- Bell, Kent, Cloyd, Withrow Family Collection, 1780/199830
- Wharton and Radford Families Papers, 1783/190612
- Dillard-Larkin Family Papers, 1809/195511
- Smithfield Preston Foundation Papers, 1784/188110
- Dickson Family Papers, 1769/19247
- Black, Kent, and Apperson Family Papers, 1779/19846
- Preston Family (Alice Preston Moore Collection) Papers, 1749/18826
- Stearns Family Papers, 1714/19206
- Historical Maps Collection, 1500/20235
- John Nicolay Papers, 1782/19835
- Pauline E. Burks Family Papers, 1763/19855
- Anna Burton Ellett Collection, 1751/19324
- Bailey-Law Collection, 1825/19714
- Dorothy McCombs Collection,, 1970/19894
- Henry Iddings Family Collection, 1810/19004