- Cazenove Family Papers (MS212), 1786/19703
- Charles Brown Papers, 1792/18885
- Charles Campbell Papers, 1743/18967
- Childress Family Papers
1823-19301
- Christopher Tompkins Papers, 1778/18381
- Clark Family Papers
1804-19643
- Cocke Family Papers,
1725-1939273
- Cocke and Related Family Papers,
ca.1773-19924
- Coleman, Twigg, McEwen, and Houston
Family Papers
1814-19451
- Corie Lynn Dorset Rivers Collection of Ludwell-Lee-Slater Family Papers, 1805/19231
- Cumming Family Papers
1777-19842
- Dangerfield Lewis papers, 1799/18544
- Duke Family Papers
1764-19834
- Earl L. Core (1902-1984) Papers, 1756/19851
- Edward "Teddy" Bolton Tucker Papers, 1760/2007, bulk 1800/190079