- Duncan Green Campbell Papers, 1789/18251
- Elisha Franklin Paxton papers, 1808/1981, bulk 1853/18632
- Francis McFarland Papers, 1815/18711
- Francis P. Gaines Papers, 1803/19791
- Franklin Society records, 1801/18917
- George A. Baxter Family papers, 1797/19189
- George Washington collection, 1775/19491
- Georgia Collection, 1806/18721
- Graham Philanthropic Society records, 1809/19422
- Henry Ruffner collection, 1815/18675
- Jacob Fuller scrapbook, 1774/18782
- James Lewis Howe Papers, 1893/19511
- John C. Calhoun correspondence, 1818/18342
- Joseph H. Hennage Scripophily Collection, 1800/19501
- Land Grants, 1749/19852