- Aaron Harmon Collection (MS249), 1815/18361
- Alexandria Black Family Reunion Digital Collection, 1937/20051
- Alexandria History Collection (MS240), 1767/200812
- Alexandria Library Company Records (MS002), 1794/20079
- Alexandria, Virginia City Records (MS019), 1750/1983, bulk 1825/18751
- Armistead Boothe Papers (MS164), 1803/19902
- Cazenove Family Papers (MS212), 1786/197018
- Edith Moore Sprouse Papers (MS313), 1960/20031
- Eleanor Lee Templeman Collection (MS061), 1810/19903
- Esther Holliday Green Collection (MS073), 1859/19824
- Ethelyn Cox Collection (MS287), 1956/19801
- Helen Norris Cummings Papers (MS072), 1865/19491
- John K. Pickens Papers (MS057), 1964/19762
- John Thomas Ricketts Papers (MS071), 1787/19041
- Kennedy-Barton Book Collection (MS277), 1753/18341