- Alexandria History Collection (MS240), 1767/20081
- Alexandria Library Company Records (MS002), 1794/20071
- Alexandria, Virginia City Records (MS019), 1750/1983, bulk 1825/18751
- Armistead Boothe Papers (MS164), 1803/19901
- Cazenove Family Papers (MS212), 1786/19701
- John Thomas Ricketts Papers (MS071), 1787/19041
- Kennedy-Barton Book Collection (MS277), 1753/18341
- Lyceum Construction Records (MS245), 1790/18591
- Mary Louisa Slacum Benham Papers (MS062), 1802/18841
- McKnight, Piercy, and Jacobs Collection (MS051), 1792/19731
- Milton Penn Collection (MS267), 1794/18931
- Ramsay Family Papers Collection (MS012), 1742/19601
- Relief Truck and Engine Co. #1 Collection (MS130), 1788/19241
- Shakes Letter Collection (MS005), 1778/20151
- Thomson Mason Papers (MS135), 1804/19121