- Bell, Kent, Cloyd, Withrow Family Collection, 1780/19981
- Benjamin Stoddert Ewell Papers, 1784/1934, bulk 1830/18925
- Berkeley Family Papers
1536-present4
- Blair, Banister, Braxton, Horner, Whiting Papers, 1760/1890, bulk 1765/18173
- Bradley T. Johnson Papers
1676-19372
- Braxton County (W. Va.) Court Records and Miscellaneous Papers, 1830/19531
- Brooke County (W. Va.) Court Records and Miscellaneous Papers, 1780/191810
- Bryan Family Papers
1770-191810
- Bushrod Washington family papers, 1662/18352
- Cabell Family Papers, 1693/1913, bulk 1743/18234
- Campbell Family Papers, 1726/192015
- Carr-Cary Family Papers
1785-18394
- Carter Family Papers, 1667/1862, bulk 1792/186114
- Cazenove Family Papers (MS212), 1786/19702
- Charles and Thomas Frankland record books, 1740/18111