- Earhart Family Papers3
- Earl Gregg Swem Genealogy Collection5
- Earl L. Core (1902-1984) Papers12
- Easton-Avery Community History1
- Edgar E. MacDonald papers1
- Edith Moore Sprouse Papers (MS313)1
- Edmonds Family Papers1
- Edward "Teddy" Bolton Tucker Papers99
- Edward D. Bayles, Collector, Land Grants1
- Edward Vitale violin music collection1
- Edwin W. Lynch Vietnam War protest collection6
- Eileen Peters, Compiler, Genealogy23
- Eldon Bowman collection of Bowman family papers3
- Eldon Tucker, Collector, Chadwick, Miller, Hall, and Lazier Indentures of Monongalia County, Virginia1
- Elise S. Billmyer, Collector, Papers1