- Alexandria History Collection (MS240), 1767/200812
- Alexandria Library Company Records (MS002), 1794/20077
- Alexandria, Virginia City Records (MS019), 1750/1983, bulk 1825/18751
- Cazenove Family Papers (MS212), 1786/19709
- Edith Moore Sprouse Papers (MS313), 1960/20031
- Esther Holliday Green Collection (MS073), 1859/19823
- Ethelyn Cox Collection (MS287), 1956/19801
- Helen Norris Cummings Papers (MS072), 1865/19491
- John Thomas Ricketts Papers (MS071), 1787/19041
- Kennedy-Barton Book Collection (MS277), 1753/18341
- Lyceum Construction Records (MS245), 1790/18591
- McKnight, Piercy, and Jacobs Collection (MS051), 1792/19731
- Milton Penn Collection (MS267), 1794/18934
- Penny C. Morrill Collection (MS104), 1970/19804
- Ramsay Family Papers Collection (MS012), 1742/19601