- Austin-Twyman Papers, 1765/19396
- Blow Family Papers, 1613/1960, bulk 1770/18751
- Borland Family Papers, 1771/19403
- Brown, Coalter, Tucker Papers (I), 1790/19296
- Carter Family Papers, 1667/1862, bulk 1792/186113
- Edward "Teddy" Bolton Tucker Papers, 1760/2007, bulk 1800/19002
- Henkel Family Papers, 1783/18741
- Jerdone Family papers, 1753/18905
- John Marshall Papers, 1755/18353
- Manuscripts - Geographic Names, Business Names and Subjects, 1725/19492
- Philip Lightfoot Papers, 1778/18002
- Richard Billups Papers, 1705/1857, bulk 1774/18221
- Skipwith Family papers, 1760/19771
- Tucker-Coleman papers, 1664/1945, bulk 1770/19071
- Virginia Cities Collection, 1663/19801