- Alexander, Fultz, and Willson Families Collection, 1770/19701
- Alexandria History Collection (MS240), 1767/200810
- Alexandria, Virginia City Records (MS019), 1750/1983, bulk 1825/18751
- Allen Family Papers, 1766/19333
- Ancella Bickley, Historian, Research Papers regarding African-Americans, 1775/2018, bulk 1970/20114
- Anderson Family papers, 1755/19584
- Andrew Delmar Hopkins Papers, 1787/19431
- Andrew Lindamood papers, 1768/18172
- Andrew Reid Account Book, 1787/18372
- Ann Sparshall Commonplace Book, 1783/17922
- Anna Burton Ellett Collection, 1751/19324
- Anne Atkinson Chamberlayne Collection., 1742/19631
- Anthony Ware, Miscellaneous Papers, 1773/18861
- Archibald Stuart Ledgers, 1757/18521
- Archibald Woods Papers, 1777/1846, bulk 1783/184611