- Administration records collection, 1776/19761
- Alexander, Fultz, and Willson Families Collection, 1770/19701
- Anderson Family papers, 1755/19581
- Baer Family Papers, 1744/19291
- Board of Trustees records, 1774/19661
- Brady Family Papers, 1750/19801
- Christopher A. Dorrance collection, 1750/20001
- George Washington collection, 1775/19491
- Henry Lee III papers, 1779/18131
- Jacob Fuller scrapbook, 1774/18781
- Land Grants, 1749/19851
- Lee-Jackson Foundation collection, 1775/19131
- Legal Documents, 1742/18951
- Manuscript leaves from the Qur'an and Dala'il al-Khayrat, 1700/19001
- Mining Industry, 1000/20001