- W. Jett Lauck papers, 1900/19522
- W. Wilson Notebook, 1755/17992
- Wade Hampton Frost papers, 1880/19844
- Waller family papers, 1677/19651
- Wallpaper collection, 1757/18401
- Walter Jones Papers, 1721/17672
- Washington and Custis Families account book, 1757/17732
- Washington and Lee University and Regional Virginia History Research Collection, 1609/20163
- Watts family papers-addition, 1786/19501
- Webb-Prentis Family Papers
1770-19088
- Webb-Prentis Family Papers, 1735-19424
- West Virginia Land Grants Records, 1748/19124
- West Virginia Naturalization Records, 1814/19911
- Wickham family papers, 1704/19503
- Wilkin Family Papers, 1757/1922, bulk 1780/18708