- Taylor collection of Lewis family papers, 1700/19501
- Ted and Mary Wendell early American collection, 1721/18261
- Terrill-Porterfield Families, Papers regarding the Civil War and Other Material, 1716/1994, bulk 1840/19201
- The Independent Collection, 1680/19602
- The Thirty Fifth State, Manuscript and Galley, 1609/19601
- The University of Virginia Collection on the History of Childhood, Parenting, and Family Building., 1700/20143
- Thomas Fairfax Land Grant, 17501
- Thomas G. and Louise Rowe Pullen Collection, 1655/17916
- Thomas Harrison correspondence, 1716/17571
- Thornton Tayloe Perry, Collector, Papers, 1732/19651
- Thruston family commonplace book, 1604/19251
- Tisinger Family collection of Shenandoah County land surveys, 1749/19321
- Title Transcription: Alexander Mackay-Smith Collection, 1689/182711
- Tucker-Coleman papers, 1664/1945, bulk 1770/19079
- Tyler Family Papers, Group A, 1716/19463