- Charles and Thomas Frankland record books, 1740/18111
- Christian S. Hutter miscellany, 1602/19451
- English and American legal documents, 1559/18471
- European figure engravings, 1535/18491
- John Gottfried Watenbach calligraphic sample book, 1748/17721
- Livre pour la remede pour les chevaux [Book of the remedy for horses], 1741/17601
- Papers of the Randolph Family of Edgehill, 1732/18601
- Quinby, Teackle, and Upshur families of Somerset County, Maryland, and Accomack and Northampton Counties, Virginia Papers, 1713/19771
- Robert and Ruth Carroll artifact and book collection, 1728/19401
- The University of Virginia Collection on the History of Childhood, Parenting, and Family Building., 1700/20141
- Thomas Harrison correspondence, 1716/17571
- Thruston family commonplace book, 1604/19251
- University of Virginia Medical Illustrations collection, 1720/1969, bulk 01
- Von Frieling's Salve collection, 1512/1977, bulk 1900/19321
- Wickham family papers, 1704/19501