- George Washington collection, 1654/17991
- Hampshire County (W. Va.) Court Records and Miscellaneous Papers, 1736/19492
- Hart collection, 1762/19391
- Hickory Neck Church records, 1721/20241
- Hill Family Genealogy, 1700/1999, bulk 1980/19992
- Historic Map and Government Documents Collection, 1630/19781
- Historic Maps of Europe, 1572/18451
- Historic ephemera collection, 1796/19861
- Jack Sandy Anderson, Compiler, Local History Articles and Genealogy Papers, 1600/2011, bulk 2000/20081
- James M. Guiher, Jr., Papers, 1835/2014, bulk 1927/19761
- Jerdone Family papers, 1753/18902
- Jim Comstock, Newspaper Editor and Collector, Papers, 1650/2003, bulk 1850/19953
- Lexington Arsenal and Virginia Militia records, 1702/18391
- Margaret Grattan Weaver collection, 1707/1992, bulk 1857/19101
- Maupin-Washington Papers, 1732/19322