- Map of Scotland, 1708, 17081
- Margaret Forbes Brand, Compiler, Genealogies, 1500/19651
- Margaret Grattan Weaver collection, 1707/1992, bulk 1857/19102
- Marshall W. Fishwick Collection, 1700/2007, bulk 1923/20072
- Mason C. Andrews Papers, 1777/2010, bulk 1950/19901
- Mercer County History, 1700/19351
- Methodist Files, 1784/20241
- Mining Industry, 1000/20001
- Morley Jeffers Williams Collection, 1602/19673
- Morton Genealogy Collection, 1830/19784
- Museums at Washington and Lee records, 1649/20161
- Naval Account Book, 1660/17112
- Northern Neck Collection, 1672/19361
- Office of the President. James Blair Records, 1695/17473
- Ollen Lawrence Burnette, Jr. papers, 1815/20141