- A. E. Dick Howard papers, 1928/20171
- Archibald Stewart Notebook, 17051
- Blow Family Papers, 1613/1960, bulk 1770/18751
- Board of Visitors records, 1757/20231
- Cabell Family Papers, 1693/1913, bulk 1743/18231
- Carter Family Papers, 1667/1862, bulk 1792/18612
- Channing Moore Hall Papers, 1920/1953, bulk 1930/19531
- Christian S. Hutter miscellany, 1602/19457
- Dunmore Family Papers (I) [in part photocopies], 1650/18993
- Edgar E. MacDonald papers, 1933/19931
- Edwin W. Lynch Vietnam War protest collection, 1965/19756
- Eileen Peters, Compiler, Genealogy, 1887/199512
- Elizabeth Fairfax cookbook, 1694/17951
- Ephemera Collection, 1800/20141
- Esther Holliday Green Collection (MS073), 1859/19821