- Armistead-Cocke Papers, 1680/19171
- Bushrod Washington family papers, 1662/18352
- Cabell Family Papers, 1693/1913, bulk 1743/18231
- Carol R. Lubin papers, 1960/19812
- Carter Family Papers, 1667/1862, bulk 1792/18611
- Elizabeth Fairfax cookbook, 1694/17951
- George Washington collection, 1654/17991
- Hill Family Genealogy, 1700/1999, bulk 1980/19991
- Historic Map and Government Documents Collection, 1630/19781
- Historic Maps of Europe, 1572/18451
- Jack Sandy Anderson, Compiler, Local History Articles and Genealogy Papers, 1600/2011, bulk 2000/20081
- James M. Guiher, Jr., Papers, 1835/2014, bulk 1927/19761
- Jerdone Family papers, 1753/18901
- Jim Comstock, Newspaper Editor and Collector, Papers, 1650/2003, bulk 1850/19951
- Morley Jeffers Williams Collection, 1602/19672