- Blow Family Papers, 1613/1960, bulk 1770/18753
- Bruton Parish Church (Williamsburg, Va.) records, 1662/2010, bulk 1900/20003
- Bushrod Washington family papers, 1662/18353
- Cabell Family Papers, 1693/1913, bulk 1743/18233
- Chester McNerney Collection, 1290/19503
- Elizabeth Fairfax cookbook, 1694/17953
- George Washington collection, 1654/17993
- Jack Sandy Anderson, Compiler, Local History Articles and Genealogy Papers, 1600/2011, bulk 2000/20083
- Jim Comstock, Newspaper Editor and Collector, Papers, 1650/2003, bulk 1850/19953
- King William III and Queen Mary II Papers, 1689/17103
- Morley Jeffers Williams Collection, 1602/19673
- Performing arts manuscripts collection, 1475/19843
- Randolph H. Lytton Historical Virginia collection, 1670/20043
- Robert Hunt Land Papers, 1938/19423
- Roy Bird Cook (1886-1961), Collector, Papers, 1679/1984, bulk 1840/19603