- Chester McNerney Collection, 1290/19502
- English Receipt and Home Remedy Manuscript Book, 1665/17042
- George Washington collection, 1654/17992
- Hill Family Genealogy, 1700/1999, bulk 1980/19992
- Historic Map and Government Documents Collection, 1630/19782
- Historic manuscript collection, 1601/19332
- Historic map collection, 1675/19712
- James M. Guiher, Jr., Papers, 1835/2014, bulk 1927/19762
- John Womack Wright Collection of Maps, 1675/19182
- Latane Family Papers
1650-18982
- Latin Exercise Book, 1672/17212
- Naval Account Book, 1660/17112
- Randolph H. Lytton Historical Virginia collection, 1670/20042
- Robb-Bernard Papers, 1665/1980, bulk 1850/19502
- Saint Andrew's Society collection, 1861/19952