- James M. Guiher, Jr., Papers, 1835/2014, bulk 1927/19762
- Jan Karon papers, 1918/2018, bulk 1964/20181
- Jerdone Family papers, 1753/18901
- Jim Comstock, Newspaper Editor and Collector, Papers, 1650/2003, bulk 1850/19953
- John D. Hoblitzell, Jr. (1912-1962), Politician, Papers, 1956/19621
- John W. Warner papers, 1967/2009, bulk 1967/20081
- Latane Family Papers
1650-18982
- Lee Nicholson Papers, 1827/19385
- Lynch Family History, 1600/19401
- Manuscripts - People and Family Names, 1621/1949, bulk 18001
- Manuscripts Artifact Collection, 1800/20101
- Map Collection, 1629/19911
- Margaret Forbes Brand, Compiler, Genealogies, 1500/19651
- Mining Industry, 1000/20001
- Morley Jeffers Williams Collection, 1602/19672