- Cambridge University Charters, 1575/16691
- Channing Moore Hall Papers, 1920/1953, bulk 1930/19531
- Ephemera Collection, 1800/20141
- J. Paul Hudson Papers, 1930/19982
- Naval Account Book, 1660/17111
- Richard Lee Morton papers, 1756/2006, bulk 1930/19691
- Robb-Bernard Papers, 1665/1980, bulk 1850/19501
- Samuel H. Yonge papers, 1890/19351
- Sheet Music Collection, 1827/19742
- Thomas G. and Louise Rowe Pullen Collection, 1655/17912
- Tucker-Coleman papers, 1664/1945, bulk 1770/19072
- Tyler Family Papers, Group G, 1645/19172
- Upshur Family Papers, 1662/19361
- Virginia Cities Collection, 1663/19802
- Virginia Counties Collection, 1600/2000, bulk 1730/18905