- Lee Nicholson Papers, 1827/19386
- Morton Genealogy Collection, 1830/19784
- Tyler Family Papers, Group D, 1939/19513
- Wade Hampton Frost papers, 1880/19843
- 1828 Catalogue Project digital image collection, 2012/20192
- Baylor Family Papers
1653-19151
- Berkeley Family Papers
1536-present1
- Henkel Family Papers
1791-18851
- Henry Rose Carter papers, 1775/19471
- Latane Family Papers
1650-18981
- Manuscripts Artifact Collection, 1800/20101
- Papers of the Low Moor Iron Company
1873-19271
- Thomas G. and Louise Rowe Pullen Collection, 1655/17911
- Thruston family commonplace book, 1604/19251
- Von Frieling's Salve collection, 1512/1977, bulk 1900/19321