- 17th and 18th century British periodicals, 1600/18001
- Bevill Family Papers, 1558/1939, bulk 1558/17071
- Blow Family Papers, 1613/1960, bulk 1770/18752
- Cambridge University Charters, 1575/16692
- Channing Moore Hall Papers, 1920/1953, bulk 1930/19531
- Chester McNerney Collection, 1290/19502
- Collection of French Language Manuscripts, 1633/1942, bulk 1633/19421
- Collection of Spanish Language Manuscripts, 1551/18581
- Dunmore Family Papers (I) [in part photocopies], 1650/18991
- Ephemera Collection, 1800/20141
- Gideon Macon Family Charts, 1602/19951
- J. Paul Hudson Papers, 1930/19981
- Jerdone Family papers, 1753/18901
- Lee Nicholson Papers, 1827/19386
- Manuscripts - People and Family Names, 1621/1949, bulk 18001