- North America (Reproduction), 16501
- Paul Stevens map collection, 1541/17781
- Performing arts manuscripts collection, 1475/19841
- Raleigh (Ralegh) and Carew family correspondence, 1500/16521
- Richard G. Joynt Collection of British Manuscripts, 1593/20151
- Shenandoah County Historical Society Collection, 1147/20001
- Stanford Family Legal Papers, 1639/17201
- The Thirty Fifth State, Manuscript and Galley, 1609/19601
- Thruston family commonplace book, 1604/19251
- Tyler Family Papers, Group G, 1645/19171
- Virginia Counties Collection, 1600/2000, bulk 1730/18901
- Virginia Records, 1623/19211
- Virginia Records, 1632/19331
- Von Frieling's Salve collection, 1512/1977, bulk 1900/19321
- Washington and Lee University and Regional Virginia History Research Collection, 1609/20161