- Saint Andrew's Society collection, 1861/19952
- Sheet Music Collection, 1827/19742
- Von Frieling's Salve collection, 1512/1977, bulk 1900/19322
- W. Jett Lauck papers, 1900/19522
- Wade Hampton Frost papers, 1880/19842
- 17th and 18th century British periodicals, 1600/18001
- A. E. Dick Howard papers, 1928/20171
- Berkeley Family Papers
1536-present1
- Bevill Family Papers, 1558/1939, bulk 1558/17071
- C. Harrison Mann, Jr. Map Collection, 1579/19611
- C. Harrison Mann, Jr. map collection, 1579/19611
- Channing Moore Hall Papers, 1920/1953, bulk 1930/19531
- Collection of Spanish Language Manuscripts, 1551/18581
- English and American legal documents, 1559/18471
- European figure engravings, 1535/18491