- Historical Maps Collection, 1500/20231
- Italian legal documents, 1605/16261
- Jack Sandy Anderson, Compiler, Local History Articles and Genealogy Papers, 1600/2011, bulk 2000/20081
- Johann Georg Weidenkeller album amicorum, 1605/16201
- Lynch Family History, 1600/19401
- Margaret Forbes Brand, Compiler, Genealogies, 1500/19651
- Mining Industry, 1000/20001
- Morley Jeffers Williams Collection, 1602/19671
- Paul Stevens map collection, 1541/17781
- Performing arts manuscripts collection, 1475/19841
- Raleigh (Ralegh) and Carew family correspondence, 1500/16521
- Richard G. Joynt Collection of British Manuscripts, 1593/20151
- The Thirty Fifth State, Manuscript and Galley, 1609/19601
- Thruston family commonplace book, 1604/19251
- Virginia Counties Collection, 1600/2000, bulk 1730/18901