- John D. Hoblitzell, Jr. (1912-1962), Politician, Papers, 1956/19621
- John W. Warner papers, 1967/2009, bulk 1967/20081
- Manuscripts Artifact Collection, 1800/20101
- Margaret Forbes Brand, Compiler, Genealogies, 1500/19651
- Mining Industry, 1000/20001
- Morton Genealogy Collection, 1830/19781
- Ollen Lawrence Burnette, Jr. papers, 1815/20141
- Papers of the Low Moor Iron Company
1873-19271
- Paul Stevens map collection, 1541/17781
- Raleigh (Ralegh) and Carew family correspondence, 1500/16521
- Richard G. Joynt Collection of British Manuscripts, 1593/20151
- Richard J. DeMartino papers, 1910/19651
- Richard Lee Morton papers, 1756/2006, bulk 1930/19691
- Shenandoah County Historical Society Collection, 1147/20001
- Tyler Family Papers, Group D, 1939/19511