- John D. Hoblitzell, Jr. (1912-1962), Politician, Papers, 1956/19621
- John W. Warner papers, 1967/2009, bulk 1967/20081
- Manuscript page of Gregorian chant propers for two occasions, including the Feast of the Nativity of the Blessed Virgin Mary, from an Italian choral book, 1475/15251
- Margaret Forbes Brand, Compiler, Genealogies, 1500/19651
- Mining Industry, 1000/20001
- Ollen Lawrence Burnette, Jr. papers, 1815/20141
- Papers of the Low Moor Iron Company
1873-19271
- Performing arts manuscripts collection, 1475/19843
- Raleigh (Ralegh) and Carew family correspondence, 1500/16521
- Richard J. DeMartino papers, 1910/19651
- Richard Lee Morton papers, 1756/2006, bulk 1930/19691
- Saint Andrew's Society collection, 1861/19952
- Sheet Music Collection, 1827/19741
- The Golden Legend Folio Leaves, 1498/15272
- W. Jett Lauck papers, 1900/19522