- Henry Rose Carter papers, 1775/19471
- James Edwin Green, Photographer, Glass Plate Negatives and Other Material, 1900/1925, bulk 1900/19181
- Jan Karon papers, 1918/2018, bulk 1964/20181
- John D. Hoblitzell, Jr. (1912-1962), Politician, Papers, 1956/19621
- John W. Warner papers, 1967/2009, bulk 1967/20081
- Manuscript leaf with a miniature of St. Margaret, 1450/15001
- Manuscript page of Gregorian chant propers for two occasions, including the Feast of the Nativity of the Blessed Virgin Mary, from an Italian choral book, 1475/15251
- Medieval manuscript leaf, 1300/15001
- Mining Industry, 1000/20001
- Ollen Lawrence Burnette, Jr. papers, 1815/20141
- Papers of the Low Moor Iron Company
1873-19271
- Richard J. DeMartino papers, 1910/19651
- Richard Lee Morton papers, 1756/2006, bulk 1930/19691
- Sheet Music Collection, 1827/19741
- William Munford Tuck Papers, 1918/19681